Conservative Management of Rectal Cancer With Local Excision and Adjuvant Therapy
نویسنده
چکیده
The article by Drs. Wagman and Minsky is an excellent overview of the history, indications, treatment considerations, and comparative results of local excision alone and local excision plus chemoradiotherapy for selected distal rectal cancers. Although the literature and experience with local excision have increased, use of the technique has probably diminished over the past decade, primarily due to the groundswell of publications that lionize total mesorectal excision with low colorectal or coloanal anastomosis for most rectal cancers, as well as our inability to stage and predict nodal involvement, even in T1 cancers.
منابع مشابه
Conservative management of rectal cancer with local excision and adjuvant therapy.
The standard surgical treatment of distal, resectable, invasive rectal cancers is an abdominoperineal resection or a low anterior resection. Given the morbidity associated with these standard treatments and the frequent need for postoperative adjuvant therapy, the use of a more conservative approach, such as local excision with adjuvant therapy as primary therapy for selected cases of rectal ca...
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In their article, Drs. Wagman and Minsky provide an excellent overview of the current status of local treatment strategies for early rectal cancer. They have rightly pointed out that while minimal surgery is an attractive option, it must be balanced against the highly curable outcomes of radical surgical resection. Expanded experience with stapling devices has extended the level at which safe a...
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In their article, Drs. Wagman and Minsky provide an excellent overview of the current status of local treatment strategies for early rectal cancer. They have rightly pointed out that while minimal surgery is an attractive option, it must be balanced against the highly curable outcomes of radical surgical resection. Expanded experience with stapling devices has extended the level at which safe a...
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Because patients with locally advanced rectal cancer are at high risk for both recurrence and distant disease, they require adjuvant therapy. In the United States, the current standard of care is neoadjuvant chemoradiation followed by surgery and adjuvant chemotherapy. Neoadjuvant chemoradiation has been shown to improve local recurrence rates and decrease toxicity. However in the era of total ...
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In selected patients, local excision of rectal cancer may be an alternative to radical surgery such as abdominoperineal excision of the rectum or anterior resection. Local excision carries lower mortality and morbidity, without the functional disturbance or alteration in body image that can be associated with radical surgery. There are several techniques of local therapy for rectal cancer, with...
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